• ragebutt@lemmy.dbzer0.com
    link
    fedilink
    English
    arrow-up
    4
    ·
    6 days ago

    When I’ve worked with older trans clients spironolactone seems to be what really kickstarts hair growth, especially if they get it in before alopecia really sets in and miniaturizes follicles in a way that can’t be reversed (at least with current medications, and barring surgical intervention). Estrogen too. Either way you’re reducing the amount of androgens. As a result it can be much more effective than rogaine, which works as a vasodilator to enlarge hair follicles (probably, mechanism isn’t fully understood) or finasteride/propecia, which works by blocking androgen DHT rather than reducing it.

    I’m not familiar with research on efficacy for this purpose but I wouldn’t be surprised if it was more effective. While some people have dramatic responses to minoxidil and finasteride many have a more minor response or none at all, even.