That question came up to me, when recently working on one project I needed to restart my PC several times. And therefore, while I used 3-5 web apps I needed to log back in to each one of them again, after each restart. And I started wondering if privacy-wise that auto-clear feature is worth it or not? Has anyone maybe tested that?
The profile selector for Firefox (I use Librewolf) is a nice way to manage different settings for websites that need to keep browsing data. You can also use containers but I find alt-tabbing more easy to keep track of. Foxyproxy is good for this