I trust deaf users reporting that their needs are not being met, but I do not currently play and know the nuance myself. I’ll remove the claim if I’m wrong upon further research.

Edit: Upon further research, it seems like there is a lot of reliance on WeakAuras in the deaf community (visual cues for sound-only events that may relate specifically to combat, raid communication), and many rely on rotation helpers for understandable reasons (like neurological conditions or physical disabilities that require more focus to be put into movement). It seems like colorblind or visually-impaired users will also suffer due to the lack of ability to color-code or highlight specific buffs and debuffs.

Nameplates seem to be one of the areas where users can no longer modify with addons, I’m unsure if this also affects unit frames in some part.