I wouldn’t, I keep all of my data separate from my OS drive entirely so I can reformat or install a new OS whenever I feel like… nasty old habit from bootleg windows 7 well beyond its age, when reformatting every 6 months was good hygiene, before I found Linux… but gave me great data management insight.
IMHO there is no point backing up an OS drive, just rebuild it*.
Data is the important thing to back up because you usually can’t regenerate it.
* the corollary here is that you’ve backed up the configuration required to rebuild the OS.
I wouldn’t, I keep all of my data separate from my OS drive entirely so I can reformat or install a new OS whenever I feel like… nasty old habit from bootleg windows 7 well beyond its age, when reformatting every 6 months was good hygiene, before I found Linux… but gave me great data management insight.