I use fedora-based atomic distros for the reliability and security. Nothing else really runs SELinux out of the box and I care about security so that’s a necessary baseline. I roll my own distro though using BlueBuild, and base it off the SecureBlue image of Silverblue. Just using SecureBlue gets you nearly to what I use though
You can also run a distrobox and install stuff normally from whatever distro’s repos, then export the applications so they’re available like native. Works really seamlessly in my experience