It depends on how you’re doing it, (and how it was stored, because the molecule is pretty fragile and breaks down easily) but typically a single hit would be in the ballpark of 90-110 micrograms. So 500x would be about 0.05 grams. Which is a truly astronomical amount of LSD. Probably not the highest ever recorded, (that honor goes to a couple of idiots who thought it was cocaine and snorted it), but still a mind-meltingly high amount.
That highest dosage (while technically unknown, because we only have the ER reports when they showed up completely comatose) is estimated that they had somewhere between 1000 to 2100 hits each. And they survived. So at least Toad isn’t in danger of OD’ing.
Eight patients were seen within 15 minutes of intranasal self-administration of large amounts of pure D-lysergic acid diethylamide (LSD) tartrate powder. Emesis and collapse occurred along with signs of sympathetic overactivity, hyperthermia, coma and respiratory arrest. Mild generalized bleeding occurred in several patients and evidence of platelet dysfunction was present in all. Serum and gastric concentrations of LSD tartrate ranged from 2.1 to 26 nanograms per ml and 1,000 to 7,000 μg per 100 ml, respectively. With supportive care, all patients recovered. Massive LSD overdose in man is life-threatening and produces striking and distinctive manifestations.
A 46-year-old woman snorted a staggering 550 times the normal recreational dose of LSD and not only survived, but found that the foot pain she had suffered from since her 20s was dramatically reduced.
This Frog & Toad meme is based on a true story, apparently.
Hah, yup. In my head, I stupidly went “Milli is 10-3 so micro is 10-4.” Somehow completely skipping that “micro” means “million”. Regardless, the rest of the post is correct because I wasn’t using 5 grams as the basis for anything else.
It depends on how you’re doing it, (and how it was stored, because the molecule is pretty fragile and breaks down easily) but typically a single hit would be in the ballpark of 90-110 micrograms. So 500x would be about 0.05 grams. Which is a truly astronomical amount of LSD. Probably not the highest ever recorded, (that honor goes to a couple of idiots who thought it was cocaine and snorted it), but still a mind-meltingly high amount.
That highest dosage (while technically unknown, because we only have the ER reports when they showed up completely comatose) is estimated that they had somewhere between 1000 to 2100 hits each. And they survived. So at least Toad isn’t in danger of OD’ing.
That sounds like a sure fire way to obtain ego death.
Is there more information on these accidental mind travelers?
I went looking and found this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC1129381/?page=2
Heh, and also this:
https://www.wbaltv.com/article/woman-took-550-times-the-usual-dose-of-lsd-with-surprisingly-positive-consequences/31154339
This Frog & Toad meme is based on a true story, apparently.
Might want to check your math there. 500 x 90-110 millionths of a gram is not 5 grams.
Hah, yup. In my head, I stupidly went “Milli is 10-3 so micro is 10-4.” Somehow completely skipping that “micro” means “million”. Regardless, the rest of the post is correct because I wasn’t using 5 grams as the basis for anything else.