Apparently Ms. Paint forgot to read the wiki page:

The American Heritage Book of English Usage states, “Using Ms. obviates the need for the guesswork involved in figuring out whether to address someone as Mrs. or Miss: you can’t go wrong with Ms. Whether the woman you are addressing is married or unmarried, has changed her name or not, Ms. is always correct.”

(Emphasis mine)

Since he didn’t guess that Ms stood for something, maybe he also couldn’t guess that Mr stands for something?

part of why he’s being splashed, it’s a lame pickup line for more than one reason.