I no longer get excited about medical innovation because I know I’ll never be able to afford to benefit from any of it. I’m lucky to have gotten vaccinated as a child while that was still legal for the poors
When I was a teenager it was announced that we would soon be able to stimulate the growth of brand new teeth, right in the mouth. I’m almost 50 and I need some new fuckin’ teeth real soon.
its possible now but the world is pretty fucked. we can already reduce aging too and reverse it, we have cancer treatments that have near 100 percent success rates for many cancers, and many of these developments were only in recent years but when you watch how much gets done without making it into actual hospitals because of shitass companies and practices it makes you feel a little concerned if any of that will really have an impact, especially when everything is already burning anyway…
There was a new development in japan less than a year ago. Downside is all your teeth fall out and all regrow
I’m sorry, I thought you said there was a downside.
You think teething and a soft food diet isn’t a downside? Any time I have anything done that requires soft food, I’m craving solid food within like three days. It sucks.
It didn’t sound like a big deal, but somehow you just instilled in me an existential dread of having no teeth to enjoy solid foods when craving some.
Well you can still cut it into small pieces for minimal chewing. Last time I couldn’t have solid food at all.
Given the state of my teeth, I’m not far from that anyway.
Tooth fairy isn’t unionized.
She’s ionized?
The problem is those new teeth were soft with no enamel. This could address that. Either way, no insurance will cover this and it will cost a fortune.
My teeth already have no enamel so I’m game.
No offense, but unless you have some sort of condition like not growing enamel, what have you been doing for your teeth to be that bad at not even 50? Chewing on anvils and flossing with barbed wire?
Chemo, Bruxism, Shitty genetics, mental health often leads to poor hygiene, sports or injuries can fuck you.
Bigger question is why you’re choosing to be an A-grade arsehole over it.
Playing hockey?
Bruxism. Why, what’s wrong with you? Sheesh.
If this is legit and dental industry doesn’t try to drown it in a bathtub I’ll be fucking shocked.
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Just ignore all those famous exceptions.
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When you zoom out, the invariant story of capitalism is exactly the opposite. Capitalism contains the seeds of its own destruction.
Our medical knowledge is shockingly rudimentary. Why we can’t coax cells to do what they did anyway before is something we really need to understand to pretend to have any kind of medical knowledge. What passes for medicine is nothing more than 19th century++. See this, do that, body will heal. That’s about it. I’m shocked every time I see someone in a wheelchair, how can we have LLMs and hallucinated movies but not understand how a few milligrams of organic matter organizes into nerves? etc etc etc
I am hoping that the absolutely bonkers computing power we are currently wasting on fart videos will be used to simulate matter in the future, here’s to cheering on the AI crash!
we do have the ability to coax cells and even turn differenciated cells into pluripotent stem cells we’ve been able to for years the people who did it won a nobel peace prize
In reality, AI will help solve a lot of our medical ignorance. Not the goofball LLMs, but specialized AI algorithms specifically geared towards niche medical research and applications. Don’t let GPT and Gemini sour the potential of some possibly game changing software.
The human body is an immensely complex system of chemical reactions.
And before you say “simulate it”, we don’t have nearly enough computational resources to do that. Simple reactions or chains of reactions, yes, but even a simple body process consists of multiple steps and a number of large, complex molecules.
This right here. We can definitely model how a single chemical effects cells, but what about multiple chemicals together. The reality is we are still very far from simulating something like the side effects from multiple interacting drugs at once.
We will likely discover some incredible insights when we do this though.
We have a pretty good idea how things work during development, it’s tricking those cells into the same process as a fully-formed organism that’s hard. Isolating and distributing the hormones in the right way. I think you’re underselling the complexity and scale of biology. We can’t just put a tiny camera and chemo-sensor inside a neuron and see what’s going on in real time and synthesize up a hundred thousand copies.
That’s my point, we’ll simulate it.
How many times have I read this headline…
My only question is - when will it be available?
Every time you read it it’s in a mouse or a petri dish.
I wish they would put that on the headline.
According to the article, they used human teeth from cadavers
There’s a big difference between doing something in a lab and mass producing it for millions of people.
Hell yeah. I’m gonna overuse this shit and just have 2 gigantic teeth. One on the top and one on the bottom. No more flossing for me. Fuse those bad boys together. I’ll have the smile of an N64 game character.
I think that’s just called dentures
What could PAWSIBLY go wrong?
Settle down Mitch Hedberg.
Currently sitting in an Uber relying on autocorrect to spell for me. I don’t want to belly laugh and make my driver think I’m a crazy person fuk u
Gotta get that cartoon chin as well.
if you’re gonna get chin work, make sure you have a butt chin (with a smaller, extendable butt implant installed in the cleft)
I bet the catch here is it could accidentally grow anywhere in the body as long as it mimics what our mouth has (saliva). Imagine growing enamel in our tongues or throat.
Doesn’t matter without an anchor point
How long until the dental restoration industry lobbies it out to be banned, so they can keep selling their photoshop jobs of people smiling with new teeth alongside crowns and implants, all at an inflated price?
It already happens with nano-hydroxyapatite pastes. In Europe you find them at the supermarket for 5 euro, in USA you need a prescription and it’s sold for $$$
Uh no. You can get nHA toothpaste in the USA without a prescription, not sure why you’d think that. It’s just not a popular item here so it’s not sold at brick and mortar stores for the most part, though some smaller stores have it. But I have no problem ordering the stuff online.
Maybe it changed in the recent years? I remember clearly it was forbidden by FDA for sale without prescription
Proudly “fluoride free” too, which makes me immediately doubt the veracity of their dental health claims.
“Dental enamel has a unique structure, which gives enamel its remarkable properties that protect our teeth throughout life against physical, chemical, and thermal insults,” said lead author Dr. Abshar Hasan
This man doesn’t just disapprove of people mistreating their teeth, he is personally insulted by it. A true dentist.
I could never ever work in that field, it gives me the ick. So I appreciate people who can.
Also enamel is the hardest substance in your body; AFAIK chemically it is indeed interesting and hard (ha) to emulate with other bio-safe materials.
But will it allow us to create new body armors, is what I want to know.
Simply line yourself with the teeth of your enemies (if they flossed regularly)
Hmmm maybe þe stench of þe rotting teeþ of your enemies who had poor dental hygiene would be a more effective deterrent?
If þey didn’t have poor hygiene, why were þey your enemies?
Hard is usually opposed to strong. It doesn’t take much force to break a tooth—ive done it!
You could just regrow þe armor “within weeks”.
Body Armors… Wait how do you intend on taking the teeth armor off?
Coke and Skittles, duh.
Why would you want to?
I could never ever work in that field, it gives me the ick. So I appreciate people who can.
It’s almost as bad being married to someone that works in that field.
My wife is a dental hygienist. Some of the horrific shit she sends me would turn your stomach. And then the experiences she’s had working on teeth… Just so so gross. 🤮🤮
My wife is also a dental hygienist, and she has never once sent me any horrific shit…. So I don’t think that’s a trait necessarily tied to the occupation, lol
Lucky. Can I get her number so I can have her talk to my wife? Haha
J/k lmao
Most dentists recommending eating at least 3 poop.
I feel like that should have maybe been a red flag while dating.
But I made this wonderful scarf!
Exploding abscesses… Ugh
Got a photo one time when we were dating… was hoping for tits. Nope tooth root and all. It fell out when she cleaned the years of solidified shit off it.
Granted she was in public health in a poor poor poor community but still. Gross.
Oh, man, that reminds me of one time when I cracked a tooth and couldn’t get in to see the dentist for a while. Cleaning the whatever out of the inside was so gross in smell, taste, and feeeeel, and so incredibly painful.
1/10 dentists disagree with this guy.
Hands you a bloody 2X4…not anymore!
Hopefully in the right place.
Behold my new chitinous armour plates!
Don’t give the military ideas like that.
Congrats, you’re now a narwhal
Narwhals, narwhals, swimming in the ocean
Causing a commotion 'cause they are so awesome
Side effects: sharp fangs and uncontrollable drooling.
Win win
The researchers used extracted human molars as an ex vivo model, first etching their enamel or dentine surfaces with acid to mimic different stages of tooth erosion. They then applied a single coating of the biomimetic elastin-like recombinamer (ELR) gel and let it dry. Finally, the teeth were immersed in carefully controlled mineralization baths that replicated the ionic environment of saliva.
Keep in mind this hasn’t been shown to actually help teeth in someone’s mouth.
Just from that, it seems like its a patch job, not capable of regrowing from zero.
i wouldn’t expect that from a gel
I definitely saw lots of ads on AliExpress for gels that would regrow your teeth before their algorithm realized I wasn’t there for that.
To be fair, the research is on regenerating, not regrowing. I wouldn’t expect regrowing lost teeth to be possible any time soon, unless some kind of bio 3D-printing method became available.
My guess is that they can slowly regrow lost enamel under fillings, slowly build back up later by layer until a filling is no longer needed. What would be amazing is a cure for gum disease.
Finally, my dream of making teeth anywhere you can imagine could be realized.
FINALLY vaginadentata won’t just be a pipe dream.
🎵 Vagina Dentata, what a wonderful phrase! 🎵
I hate all three of you lol
(take my hate upvotes)
Teeth growing inside tumors is already a thing. Just grow some tumors.
Imagine if teeth were like antlers where they emerge covered in skin that’s ripped off every year
Thanks for the new nightmare. I hate it.
if only you were a crocodile or shark, they replace thier teeth all the time.
those would be abnormal though, the genetics behind the tumor is probably not like a normal chromosomes(partial deletions, extra copies,etc). odontomas, and teratomas produces it but they are abnormal teeth.
Can they make one to generate beaver enamel? I will accept the red color if I can chew through a tree.
beaver have a different composition, its made of iron compounds, i dont think human mouths are adapted to have iron teeth, it might damage your other teeth, because iron is much harder than calcium hydroxyapatite.
there are times i think about getting titanium caps, but my one crown does not feel great and i don’t like how mouthpieces feel
I’ve heard of stuff like this for well over a decade. Seems like there’s a new article about teeth regrowth every month, either enamel or full teeth. Still waiting on real results.
It’s a subject that targets people’s deep-seated insecurities. Everybody wants a tooth that can regenerate when they first discover a cavity for themselves.
With enamel regrowing constantly after the smallest scratch, cavities cannot get to where they form.
This hokum story is promising no more cavities ever.
The teeth regrowth thing was only two years ago.
https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2014.00036/full
It’s been in the works for over ten years. Here is a paper on research into it from 2014.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3000521/
Here’s another one from 2010.
https://www.sciencedirect.com/science/article/pii/S1882761608000070#cesec60
And another from 2008.
At this point it’s a race between teeth, fusion and GTA 6. Place your bets, people.
I bet GTA 6, if only because those investors are going to be more bloodthirsty about it coming out eventually.
Teeth and fusion need approval to be safe from the…government…
I withdraw my bet.
GTA6 is far more achievable. Like it doesn’t even matter what they release, that would qualify. To get this out of the lab, it would have to actually work.
And fusion really isn’t happening for decades.
thats how research works unfortunately
Absolutely, which was my point. That the tooth thing wasn’t “only two years ago” it’s actually been in the research and development process for probably over 15 years at this point, with a long way to go.
The slow roll on this is disappointing. Bad teeth majorly impact quality and length of life.
Not to mention the escalating costs.It’s a half trillion dollar industry, which is over $1500/year per American. And that’s not counting dental surgery, orthodontics, etc.
It’s the new new battery tech!
But batteries consistently improve year on year, we just keep increasing the demand of our devices in lockstep because 10% more powerful! markets much better than 10% more battery life.
We have had massive improvements in batteries so that bodes well!
Battery tech is the new fusion, just 10 years away!
I fully believe most dentists would rather kill the inventor of whoever lets us regrow teeth for cheap than let it come to the light of day
Change my mind.
The only way this sees the market is if it is nerfed to require reapplication every six months.
Dentists make a lot more money off of major repairs and general maintenance than they do by replacing teeth entirely.
Oral surgeons on the other hand do make money off major repairs to damaged teeth or teeth replacements. I know people often call anyone who works on teeth a dentist, but technically they are different professions.
implants are a niche industry though, not related to general dentistry, its considered cosmetic. so its very EXPENSIVE for implants, per tooth can be thousands(3-6k or more) they would have to go toa cosmetic dentist if they want “replacement teeth, aka implants”. I only ever went to an oral surgeon for bottom wisdom tooth extraction.
plus there is one that is orifacial, which works on the jaw/ teeth, if you have a severe prognathism or overbite/underbit they can consider surgery combined with some dental procedures beforehand. i have prognathism but i never got surgery for it, wish i did when i was younger.
I have had four teeth replaced with the oral surgeon doing the screw and the dentist did the crowns. Yes it is expensive, but reasonably common, and partially covered by dental insurance.
luckily i had root canals and dont need extractions than implants, if you try to get implants on the “cheap” like less than a few thousands you wont get results, i had a family member get1 tooth for 6k, while my parents getting theres for 2-3k, not very good results, plus advertising as using new “tech”
Huh? If you could regrow a teeth with a simple solution then they would not make money off of anything except pulling them out, and prescribing luxury bone juice.
I sure af would not waste money fixing teeth I could just regrow, especially if it can regrow in place as this article suggests without the awkward missing tooth phase.
It would be like rotors on cars. Nobody resurfaces them anymore - they just replace because replacing has become so cheap that there is no point.
But you do replace your brake pads before the wear out completely instead of just letting them grind your rotors, right?
Most dentist visits are like oil changes and vehicle checks to make sure things aren’t going to fail catastrophically.
You would be surprised how many people already don’t maintain their teeth and they aren’t replaceable yet for non ferrets.
It would be really incredible if they can manage to make this an OTC offering. This is huge.
After reading that article, this feels like something that I would want a trained professional to oversee.
Maybe similar to fluoride, there can be a low-concentration version OTC, with the strong professional version only being available directly.
No, I shall grow myself an enamel tusk!
or have beaver teeth, made of iron compound instead of calcium.
Someone will 100% create two big uniteeth.
I kind of wanted to make a Tiktok series that was how many days of brushing my teeth with nano hydroxyapatite calcium powder will it take until they are two solid Uni teeth like a cartoon?
Because if it’s really the same thing as what teeth are made of, how does it know where the end of the enamel is? Shouldn’t your teeth keep adding mass?
